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Target Corp. engages in the operation and ownership of general merchandise stores. It offers food and general merchandise, clothing and household goods, electronics, and toys. Its brands include A New Day, All in Motion, Art Class, Auden, AVA & VIV, Boots and Barkley, Brightroom, Bullseye's Playground, Casaluna, Cat & Jack, Cloud Island, Colsie, dealworthy, Embark, Everspring, Favorite Day, Figmint, Future Collective, Gigglescape, Good & Gather, Goodfellow & Co, Hearth & Hand with Magnolia, Heyday, Hyde & EEK! Boutique, JoyLab, Kindfull, Kona Sol, Made By Design, Market Pantry, Mondo Llama, More Than Magic, Opalhouse, Open Story, Original Use, Pillowfort, Project 62, Room Essentials, Shade & Shore, Smartly, Smith & Hawken, Sonia Kashuk, Spritz, Sun Squad, Threshold, Universal Thread, up&up, Wild Fable, Wondershop, Xhilaration, California Roots, Casa Cantina, The Collection, Headliner, Jingle & Mingle, Rosé Bae, Photograph, SunPop, and Wine Cube. The company was founded by George Draper Dayton in 1902 and is headquartered in Minneapolis, MN.

Target Corp

Target ($TGT) is trending as investors assess its potential turnaround, focusing on its attractive valuation and upcoming earnings report. Community members are weighing the impact of restructuring and cost-cutting measures, while noting the dividend yield. Bullish sentiment is building, with some anticipating a run toward higher price targets amid broader discussions of retail sector dynamics.

Kazia Therapeutics Ltd. is an oncology-focused biotechnology company, which engages in the business of pharmaceutical drug development. It focuses on its Paxalisib program, which is designed to treat brain cancer. The company was founded by Graham Edmund Kelly in March 1994 and is headquartered in Sydney, Australia.

Kazia Therapeutics Limited - ADR

Kazia Therapeutics

KZIA is trending due to positive initial results from a Phase 1b trial for triple-negative breast cancer, showing a significant reduction in tumor cells. The community is discussing the potential of paxalisib, combined with Keytruda and chemotherapy, to become a game-changer in cancer treatment. Some are closely watching for potential dilution, while others are optimistic about upcoming milestones and strategic partnerships.

Tonix Pharmaceuticals Holding Corp. is a clinical-stage biopharmaceutical company, which focuses on the discovery, acquisition, and development of small molecules and biologics to treat and prevent human disease and alleviate suffering. Its portfolio includes TNX-102 SL, TNX-601, TNX-801, and TNX-1800. The company was founded by Seth Lederman and Donald W. Landry on November 16, 2007 and is headquartered in Chatham, NJ.

Tonix Pharmaceuticals Holding Corp

TNXP is trending following the announcement of an increase to its share repurchase program, authorizing up to $35 million. The community is actively debating the potential impact of the buyback, especially in light of past dilution and a commercial product launch. Sentiment is mixed, with some bulls optimistic about a turnaround and potential short squeeze, while bears remain skeptical of management.

Lowe's Companies, Inc. engages in the retail sale of home improvement products. The firm offers products for maintenance, repair, remodeling, home decorating, and property maintenance. It also provides home improvement products in the following categories: appliances, seasonal & outdoor living, lumber, lawn & garden, kitchens & bath, hardware, building materials, millwork, paint, rough plumbing, tools, electrical, flooring, and décor. The company was founded in 1946 and is headquartered in Mooresville, NC.

Lowe`s Cos., Inc.

Lowe's Companies, Inc.

Lowe's is trending following the release of its latest earnings report, which beat expectations despite a mixed outlook for the year. Community discussion revolves around the company's performance relative to competitor Home Depot and its ability to navigate a challenging home improvement market. Investors are also weighing the impact of potential interest rate cuts and the company's strategic initiatives, including investments in AI and the Pro segment.

NVIDIA Corp. engages in the design and manufacture of computer graphics processors, chipsets, and related multimedia software. It operates through the following segments: Graphics Processing Unit (GPU) and Compute & Networking. The Graphics segment includes GeForce GPUs for gaming and PCs, the GeForce NOW game streaming service and related infrastructure, Quadro and NVIDIA RTX GPUs for enterprise workstation graphics, virtual GPU, or vGPU, software for cloud-based visual and virtual computing, automotive platforms for infotainment systems, and Omniverse Enterprise software for building and operating metaverse and 3D internet applications. The Compute & Networking segment consists of Data Center accelerated computing platforms and end-to-end networking platforms including Quantum for InfiniBand and Spectrum for Ethernet, NVIDIA DRIVE automated-driving platform and automotive development agreements, Jetson robotics and other embedded platforms, NVIDIA AI Enterprise and other software, and DGX Cloud software and services. The company was founded by Jen Hsun Huang, Chris A. Malachowsky, and Curtis R. Priem in April 1993 and is headquartered in Santa Clara, CA.

NVIDIA Corp

NVIDIA's earnings are the main topic, with the community anticipating a significant market reaction regardless of the outcome; many traders are expressing concerns about the sustainability of AI investments. There's also discussion around potential deals with Saudi Arabia and the impact of a possible investment in $DJT.

Sigma Lithium Corp. engages in the producing of a lithium property. It focuses its project in Minas Gerais. The firm also plans to build a world-class commercial-scale lithium concentration plant. The company was founded on June 8, 2011 and is headquartered in Sao Paulo, Brazil.

Sigma Lithium Corporation

SGML is trending as lithium prices show signs of recovery, sparking optimism among investors. Community discussions revolve around the stock's potential for further gains, with some anticipating a continued upward trajectory. Bullish sentiment is fueled by speculation around production updates and the company's connection to global lithium pricing.

What is the project about?   Horizen is a modular privacy-first platform designed to make privacy technology, such as zero-knowledge proofs and TEEs accessible and usable across the web. Originally launched in 2017 as a fair launch, non-ICO project, Horizen is now undergoing a major evolution with the launch of Horizen 2.0, a next-generation Layer 3 (L3) appchain deployed on Base, the Ethereum Layer 2 developed by Coinbase.  Horizen 2.0 is built as an Ethereum-aligned Layer 3 appchain on Base, inheriting Ethereum's security while implementing its own application-level integrity guarantees.    Key components of Horizen’s security model include:  Ethereum-Aligned Security: As an appchain deployed on Base, Horizen 2.0 benefits from Base’s rollup security and settlement on Ethereum, ensuring robust finality and composability with other L2 and L3 applications.  Simplified and Secure Architecture: Unlike Horizen’s previous iterations (which used a hybrid PoW/PoS model), Horizen 2.0 focuses on application-level security, decentralization of its privacy layers, and composability with existing infrastructure — reducing complexity and increasing user safety.  Decentralized Privacy Stack: Horizen’s focus on decentralizing privacy infrastructure (e.g., decentralized proof generation) allows for modular, secure applications that uphold data confidentiality without compromising performance.    What makes your project unique?  Privacy-first Approach: Horizen integrates a diverse stack of privacy-enhancing technologies (PETs) — including zero-knowledge proofs (ZKPs), trusted execution environments (TEEs), attribute-based encryption (ABE), multi-party computation (MPC), and fully homomorphic encryption (FHE) — to deliver scalable, flexible, and future-ready privacy solutions across its platform.  First Privacy Appchain on Base: As an L3 on Base, Horizen benefits from Ethereum’s security and Base’s scalability, while enabling a privacy layer for any app on the network. This unlocks new possibilities for private identity, DeFi, onchain gaming, and compliant confidential transactions.  Zero-Knowledge, Without the Trade-Offs: Horizen 2.0 scales ZK privacy and verification by integrating with leading zk infrastructure providers such as Fermah, zkVerify, and Singularity, optimizing proof generation for performance, cost-efficiency, and developer usability.  Token Utility Expansion: ZEN’s updated tokenomics allocates 5 million unminted tokens toward strategic ecosystem growth. ZEN powers DAO governance, serves as a payment token in privacy apps, and supports a sustainability fund to accelerate privacy innovation.  Developer-Centric Design: With EVM compatibility, privacy-friendly tooling, and the ability to embed privacy directly into smart contracts, Horizen allows developers to build privacy-first apps without requiring deep cryptographic expertise.  DAO-Led Governance: Governed by the Horizen DAO and shaped through community proposals (ZENIPs), Horizen is evolving as a fully decentralized protocol with transparent development and decision-making.    What can your coin/token be used for?  Horizen 2.0 delivers performance, privacy, and scalability for developers building privacy-enabled and compliance-friendly applications, with significantly reduced cost and latency.  At the core of the ecosystem is ZEN, the native utility token used for governance, accessing privacy services, and fueling zkApp interactions. With its migration to Base, ZEN becomes an ERC-20 token, improving liquidity, interoperability, and composability across the broader Ethereum ecosystem.

ZenCash

ZEN Crypto is trending as traders discuss its potential following recent movements in sister cryptocurrencies, along with speculation around new platform listings and regulatory compliance for this privacy coin. Community members highlight ZEN's limited supply and potential for significant price appreciation. Discussions also include technical analysis, potential breakouts, and comparisons to similar tokens.

Constellation Energy Corp. engages in the generation, supply, and marketing of clean electricity, and renewable energy products and solutions. The firm also offers wholesale energy, retail products and services. It operates under the following geographical segments: Mid-Atlantic, Midwest, New York, Electric Reliability Council of Texas (ERCOT), and Other Power Regions Segment. The company was founded in 1960 and is headquartered in Baltimore, MD.

Constellation Energy Corporation

Constellation Energy Corp

Constellation Energy is trending after securing a 20-year deal with Meta to power its AI data centers with nuclear energy, highlighting the increasing demand for reliable, carbon-free power. While analysts are optimistic about the deal, some caution that the terms may not be as beneficial as initially perceived, contributing to community discussion around the stock's valuation. The news underscores the broader context of nuclear energy playing a critical role in meeting the growing power needs of AI and data infrastructure.

Madrigal Pharmaceuticals, Inc. engages in the development and commercialization of innovative therapeutic candidates for the treatment of cardiovascular, metabolic, and liver diseases. Its lead product, MGL-3196, is used for the treatment of non-alcoholic steatohepatitis and familial hypercholesterolemia. The company was founded by Rebecca A. Taub, Frederick Bernard Craves, and Edward Chiang on March 10, 2000 and is headquartered in West Conshohocken, PA.

Madrigal Pharmaceuticals Inc

Madrigal Pharmaceuticals ($MDGL) is trending amid speculation of a potential buyout, driven by its leading position in the MASH (metabolic dysfunction-associated steatohepatitis) market and positive analyst ratings. The community is actively discussing potential acquirers and the impact of recent GLP-1 drug approvals on Madrigal's market share.  Discussions also focus on the company's growth potential, revenue projections, and upcoming catalysts, such as EU approval.

Brookfield Asset Management Ltd. engages in the provision of alternative asset management services across renewable power and transition, infrastructure, private equity, real estate, and credit industry. It invests client capital for the long term with a focus on real assets and essential service businesses. The company was founded on July 4, 2022, and is headquartered in New York, NY.

Brookfield Asset Management Ltd - Ordinary Shares - Class A

Brookfield Asset Management Inc. - Ordinary Shares - Class A

Brookfield Asset Management is trending amid news of its strategic investment in AI infrastructure, including a recently announced AI fund and partnerships with Nvidia and the Kuwait Investment Authority. Community discussions focus on the potential of this investment and its impact on BAM's growth trajectory, particularly within the context of long-term secular trends and energy transition. Some analysts have updated their ratings and price targets in response to Brookfield's activity in the nuclear and AI sectors.

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Wall Street Analysts Think Rapport Therapeutics, Inc. (RAPP) Could Surge 104.47%: Read This Before Placing a Bet

The average of price targets set by Wall Street analysts indicates a potential upside of 104.5% in Rapport Therapeutics, Inc. (RAPP). While the effectiveness of this highly sought-after metric is questionable, the positive trend in earnings estimate revisions might translate into an upside in the stock.

Rapport Therapeutics (NASDAQ:RAPP) Releases Earnings Results, Beats Expectations By $0.06 EPS

Rapport Therapeutics (NASDAQ:RAPP - Get Free Report) issued its quarterly earnings results on Thursday. The company reported ($0.71) EPS for the quarter, topping analysts' consensus estimates of...

Rapport Therapeutics (NASDAQ:RAPP) Stock Price Expected to Rise, Citizens Jmp Analyst Says

Citizens Jmp boosted their target price on Rapport Therapeutics from $77.00 to $80.00 and gave the company a "market outperform" rating in a research report on Friday...

RAPP Stock Soars 62% in a Week on Meeting Phase II Epilepsy Study Goal

Rapport Therapeutics stock jumps 62% in a week as mid-stage study of RAP-219 meets goals in drug-resistant epilepsy patients.

Rapport Therapeutics, Inc. (RAPP) on Monday said that a mid-stage clinical trial of RAP-219 in patients with drug-resistant focal onset seizures demonstrated a statistically significant reduction in long episodes over the 8-week treatment period.RAP-219 also <a target="_blank" rel="noopener noreferrer nofollow" href="https://investors.rapportrx.com/news-releases/news-release-details/rapport-announces-positive-topline-results-phase-2a-clinical">demonstrated</a> a statistically significant and clinically meaningful reduction in seizures accompanied by physical signs compared with baseline in the study, the company said, while adding that it plans to advance the investigational therapy into two late-stage trials in the third quarter of 2026.On Stocktwits, retail sentiment around <a href="https://stocktwits.com/symbol/RAPP">RAPP stock</a> stayed within ‘extremely bullish’ territory over the past 24 hours, while message volume stayed at ‘extremely high’ levels. Shares of the company traded 204% higher in the pre-market session at the time of writing.<figure class="image"><img style="aspect-ratio:575/61;" src="https://news.stocktwits-cdn.com/Screenshot_2025_09_08_at_8_06_25_AM_png_a5918d7983.webp" alt="RAPP's Sentiment Meter and Message Volume as of 8:15 a.m. ET on Sept. 8, 2025 | Source: Stocktwits" width="575" height="61"><figcaption>RAPP's Sentiment Meter and Message Volume as of 8:15 a.m. ET on Sept. 8, 2025 | Source: Stocktwits</figcaption></figure>A Stocktwits user sounded optimistic, saying the update is ‘great news.’<stembedurl>https://stocktwits.com/Mushichka/message/627808704</stembedurl>Another user, however, expressed doubts about whether the data warrants the massive rally.<stembedurl>https://stocktwits.com/Trader_Tom/message/627805877</stembedurl>H.C. Wainwright subsequently raised its price target on Rapport to $34 from $31 while keeping a ‘Buy’ rating on the shares. The firm states that RAP-219 surpassed its "most bullish expectations" and added that the data provides "unimpeachable evidence" of the drug's effect, offering "strong evidence that it has the potential to become a mainstay" in the treatment of focal onset seizures. The firm increased its probability of success for oral RAP-219 to 66% and its peak revenue estimate to $766 million, up from $613 million.Focal onset seizures are seizures that begin in one area of one brain hemisphere, causing symptoms that typically affect one side of the body or are limited to a specific sensation, emotion, or movement. In the trial, Rapport enrolled 30 patients, 18 men and 12 women, with focal onset seizures who had an implanted RNS System, a brain simulation device for drug-resistant focal epilepsy. The patients received 0.75 mg of RAP-219 oral tablets daily for 5 days, followed by 1.25 mg of RAP-219 oral tablets daily for the remainder of the 8-week treatment period.During the treatment period, over 85% patients achieved more than or equal to 30% reduction in long episodes from baseline, the company said, while 72% achieved more than or equal to 50% reduction. Twenty-four patients also achieved seizure freedom, the company said. Reduction in long episodes (LEs) is an objective electrographic biomarker for clinical seizure reduction, it said.RAP-219 was generally well-tolerated in the trial, with the majority of treatment-emergent adverse events being mild and a low discontinuation rate, the company added.Rapport plans to hold an end-of-mid-stage trial meeting with the U.S. Food and Drug Administration (FDA) in the fourth quarter of 2025. The company also expects to present additional efficacy analyses and 8-week follow-up results in 2026 and to initiate a trial to evaluate the long-term safety of the therapy in patients by the end of 2025. RAP-219 is also being evaluated in bipolar mania and diabetic peripheral neuropathic pain.RAPP stock is down 19% this year and approximately 27% over the past 12 months.&nbsp;Read also: <a href="https://stocktwits.com/news-articles/markets/equity/pnc-to-buy-colorado-first-bank-for-4-1-b-in-push-to-bolster-national-reach/chwWxbxRdrR">PNC To Buy Colorado’s FirstBank for $4.1B In Push To Bolster National Reach: Report</a>For updates and corrections, email newsroom[at]stocktwits[dot]com.

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Rapport Therapeutics Stock Rockets 204% Pre-Market To Head Toward All-Time Highs – Here’s What Happened

The company said that it now plans to advance the investigational therapy into two late-stage trials in the third quarter of 2026. 

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Rapport Therapeutics, Inc. engages in the discovery and development of transformational small molecule medicines for patients suffering from central nervous system disorders. It develops the RAP (receptor associated proteins) technology platform. The company was founded by Steven M. Paul and David Bredt in February 2022 and is headquartered in Boston, MA.

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